Publications

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Showing posts with label tp53 mdm2. Show all posts
Showing posts with label tp53 mdm2. Show all posts
Thursday, April 22, 2021

IFN-γ Concentration, p53 and Immune Sensitivity

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IFN-γ  Dimorphic complexity between Human Leukocyte Antigen (HLA) and Killer Immune Receptor (KIR) haplotypes introduce significant challeng...
Tuesday, October 20, 2020

p53 in Transition, Covid19, Cancer and Immunity

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p53's trajectory, sensitivity and function influences different outcomes in stages of transition of developing pluripotent or embryonic ...
Wednesday, March 25, 2020

Natural Killer to Kill or Transform?

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Natural Killer cells emerge from distinct sources in embryonic development and each source of these earliest, innate immune cells confers d...
Monday, January 13, 2020

Impotent Natural Killers by Cancer Stem Cells and Ageing

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Cancer stem cells have been found, through various mechanisms to alter the sentinel function and innate, immune surveillance of Natural Kil...
Thursday, December 19, 2019

Therapeutic Coding and non-Coding DNA Relationships

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Relationships of coding and non-coding intra-gene DNA are good cause for intense research and scientific debate. Many cellular functions of...
Monday, November 25, 2019

Synapses By p53 And CD40L in Reproduction and Immunity

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Cell membranes constitute a diverse range of lipid molecules each attached to a varying, odd or even length hydrocarbon chain (a tail) tha...
Saturday, September 28, 2019

A p53 Checkpoint For Cancer Therapy

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Enormously complex signaling exists in the communication of antigens, receptors and ligands in DNA pathways between Natural Killer cell...
Wednesday, September 4, 2019

Hope for a p53 Autologous Natural Killer Cell Therapy

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Natural Killer Cells (NK) are much more than cell killers! They possess mechanisms and sensitivities that, among many functions, enables...
Tuesday, July 16, 2019

Natural Killer Shaping A Life

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As explained in previous posts , reproduction and innate immunity conspire when maternal Natural Killer (NK) cells of the decidua, lining th...